Compound Kills Chemotherapy-resistant Cancer Cells / Il composto uccide le cellule tumorali resistenti alla chemioterapia
Compound Kills Chemotherapy-resistant Cancer Cells / Il composto uccide le cellule tumorali resistenti alla chemioterapia Segnalato dal Dott. Giuseppe Cotellessa / Reported by Dr. Giuseppe Cotellessa The administration of the compound 10580 caused human GICs (red) transplanted in mice to undergo apoptosis, a type of cell death (green). / La somministrazione del composto 10580 ha fatto sì che GIC umani (rossi) trapiantati nei topi subissero l'apoptosi, un tipo di morte cellulare (verde).Credit: Hokkaido University A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells (GICs) has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity. Despite longstanding and earnest endeavors to develop new remedies, the prognosis of most glioblastoma patients undergoing chemotherapies and radiotherapies remains poor. Glioblastoma, a malignant glioma, has a median survival period of approximately