GENIO italiano Giuseppe Cotellessa

Battery generates clean power for rural users /   La batteria genera energia pulita per gli utenti rurali Segnalato dal Dott. Giuseppe Cotellessa / Reported by Dr. Giuseppe Cotellessa The reusable battery can power an LED bulb for five hours or charge a cell phone. /   La batteria riutilizzabile può alimentare una lampadina a LED per cinque ore o caricare un telefono cellulare.  Source: HiLyte Lack of access to conventional electricity supplies keeps many residents in resource-limited areas in the dark at night without the means to charge cell phones or the light needed for students to study. A new battery device engineered at École polytechnique fédérale de Lausanne, Switzerland, can offer a sustainable, affordable solution to provide power in these regions. The reusable battery is assembled with  commonly available materials  — iron, water, coffee filters and carbon felt — and can power an LED bulb for five hours or charge a cell phone. The solid compon

Novel Drug May Reverse Breast Cancer Hormone Therapy Resistance /  Un nuovo farmaco può invertire la resistenza alla terapia ormonale contro il cancro al seno. Segnalato dal Dott. Giuseppe Cotellessa /   Reported by Dr. Giuseppe Cotellessa A novel drug based on a natural compound found in broccoli, kale and other cruciferous vegetables could hold the key to reversing or even preventing resistance to breast cancer hormone therapy, new research has found. Scientists from the University of Manchester found that drug SFX-01 – which has shown promise in a phase II trial (STEM) as a treatment for secondary breast cancer that is already resistant to hormone therapy – could reverse or even prevent resistance to hormone therapy by blocking a key cancer signaling pathway (a chain of reactions within cancer cells) called STAT3. Breast cancer is the UK’s most common cancer, with around 55,000 women and approximately 370 men being diagnosed throughout the country each year. Up to 80% of

A Biomaterial-based Vaccine for Blood Cancer /  Un vaccino a base di biomateriali per il cancro del sangue Segnalato dal Dott. Giuseppe Cotellessa /  Reported by Dr. Giuseppe Cotellessa Acute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherapy has been the standard AML treatment for over 40 years, and while it often causes the cancer to go into remission, it rarely completely eliminates the cancerous cells, which then lead to disease recurrence in nearly half of treated patients. Aggressive post-remission treatments, like high-dose chemotherapy or bone marrow transplants, can reduce the chance of recurrence, but many AML patients are not healthy enough to tolerate them. Now, a new study presents an alternative treatment that has the potential to eliminate AML cells completely: an injectable, biomaterial-based vaccine that, when combined with standard chemotherapy, caused complete

Biodegradable Nerve Guide Helps Regenerate Damaged Nerves /  La guida ai nervi biodegradabili aiuta a rigenerare i nervi danneggiati Segnalato dal Dott. Giuseppe Cotellessa / Reported by Dr. Giuseppe Cotellessa Acquired nerve damage can be caused by a variety of different  factors , including but not limited to a physical injury (the most common cause) such as a sporting accident, an automobile accident or a fall, whilst diabetes, vascular conditions, autoimmune diseases, nutritional imbalances and certain infections can attack nerve tissue. The current treatment options for nerve damage are arguably sub optimal and, as a result, patients often express that they experience low quality of life and feel debilitated by their nerve damage. Recipe for regeneration A fascinating quality of the nervous system is its ability to regenerate. Peripheral nerves that have been damaged  can  grow up to a third of an inch on their own without intervention. However, if the damaged se