Coronavirus, è confermato: tutti i pazienti guariti sviluppano gli anticorpi / Coronavirus is confirmed: all healed patients develop antibodies
Coronavirus, è confermato: tutti i pazienti guariti sviluppano gli anticorpi / Coronavirus is confirmed: all healed patients develop antibodies
Segnalato dal Dott. Giuseppe Cotellessa / Reported by Dr. Giuseppe Cotellessa
I dati arrivano da uno studio cinese. Silvestri: "Una megapillola di ottimismo. La risposta del sistema immunitario dovrebbe proteggere dalla reinfezione"
Coronavirus, Rezza (Iss): "Studio cinese su anticorpi è buona notizia in funzione del vaccino"
"Seppure in quantità variabili i pazienti guariti da Covid-19 producono anticorpi contro il virus. Questo è bene perché rende affidabile la diagnosi sierologica e, se gli anticorpi fossero proteggenti, promette bene per l'immunità". E linka lo studio cinese su Nature Medicine, che conferma: a 19 giorni dai sintomi il 100 per cento dei pazienti esaminati (285) avevano sviluppato le IgG contro Sars-CoV-2. Con livelli diversi, ai quali peraltro - precisano gli autori - non corrispondevano particolari caratteristiche cliniche dei pazienti.
La differenza
Gli anticorpi IgG sono prodotti durante la prima infezione o all'esposizione di antigeni estranei e proteggono a lungo termine contro i microrganismi. La produzione di IgG - in chi ha un sistema immunitario normale - è sufficiente a prevenire una nuova infezione. La produzione di anticorpi IgG comincia quando termina invece la produzione di Igm, gli anticorpi che si attivano immediatamente quando l'organismo entra a contatto con una nuova infezione o un antigene estraneo, dando quindi una protezione per un periodo breve. È importante dunque che lo studio abbia trovato gli anticorpi deputati alla protezione più duratura.
Lo studio cinese conferma che "il nostro sistema immunitario monta una risposta anticorpale contro il virus, risposta che con tutta probabilità, basandosi sui precedenti di Sars-1 e Mers oltre che sui modelli animali di infezione da coronavirus, protegge dalla reinfezione o almeno dal ritorno della malattia. Non possiamo sapere quanto dura questa risposta ma i precedenti con virus simili suggeriscono che dovrebbe durare almeno 12-24 mesi"
Intanto smentite le notizie di seconde infezioni: erano falsi positivi
ENGLISH
The data comes from a Chinese study. Silvestri: "A megapill of optimism. The immune system's response should protect against re-infection"
Coronavirus, Rezza (ISS): "Chinese antibody study is good news for the vaccine"
"Although in varying quantities patients cured of Covid-19 produce antibodies against the virus. This is good because it makes the serological diagnosis reliable and, if the antibodies were protective, promises good for immunity". And it links the Chinese study on Nature Medicine, which confirms: at 19 days of symptoms 100% of the patients examined (285) had developed IgG against Sars-CoV-2. With different levels, to which, moreover - the authors specify - there were no particular clinical characteristics of the patients.
The difference
IgG antibodies are produced during the first infection or on exposure to foreign antigens and protect against microorganisms in the long term. The production of IgG - in those who have a normal immune system - is sufficient to prevent a new infection. The production of IgG antibodies begins when instead the production of Igm ends, the antibodies that are activated immediately when the body comes into contact with a new infection or a foreign antigen, thus giving protection for a short period. It is therefore important that the study found the antibodies responsible for the most lasting protection.
The Chinese study confirms that "our immune system mounts an antibody response against the virus, a response that in all likelihood, based on the precedents of Sars-1 and Mers as well as on animal models of coronavirus infection, protects against reinfection or at least return of the disease. We don't know how long this response lasts but the precedents with similar viruses suggest that it should last at least 12-24 months "
Meanwhile denied the news of second infections: they were false positives
The data comes from a Chinese study. Silvestri: "A megapill of optimism. The immune system's response should protect against re-infection"
Coronavirus, Rezza (ISS): "Chinese antibody study is good news for the vaccine"
"Although in varying quantities patients cured of Covid-19 produce antibodies against the virus. This is good because it makes the serological diagnosis reliable and, if the antibodies were protective, promises good for immunity". And it links the Chinese study on Nature Medicine, which confirms: at 19 days of symptoms 100% of the patients examined (285) had developed IgG against Sars-CoV-2. With different levels, to which, moreover - the authors specify - there were no particular clinical characteristics of the patients.
The difference
IgG antibodies are produced during the first infection or on exposure to foreign antigens and protect against microorganisms in the long term. The production of IgG - in those who have a normal immune system - is sufficient to prevent a new infection. The production of IgG antibodies begins when instead the production of Igm ends, the antibodies that are activated immediately when the body comes into contact with a new infection or a foreign antigen, thus giving protection for a short period. It is therefore important that the study found the antibodies responsible for the most lasting protection.
The Chinese study confirms that "our immune system mounts an antibody response against the virus, a response that in all likelihood, based on the precedents of Sars-1 and Mers as well as on animal models of coronavirus infection, protects against reinfection or at least return of the disease. We don't know how long this response lasts but the precedents with similar viruses suggest that it should last at least 12-24 months "
Meanwhile denied the news of second infections: they were false positives
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